Discussion about this post

User's avatar
Dr Warwick Powell's avatar

An important extension. There’s an opportunity for a new global education order, as I have recently argued: https://www.chinadaily.com.cn/a/202507/16/WS6876e853a31000e9a573c381.html

Expand full comment
Bill's avatar

President Bush and Congress limited fetal stem cell research.

Following that restriction on U.S. research, ChatGPT says China made the following gains:

“Here’s a timeline of key developments in China’s fetal and embryonic stem cell research during the Bush restriction years (2001–2008), focusing on work that either used fetal tissue–derived stem cells or was enabled by the absence of U.S.-style limits:

🔹 2001

• Aug 9 – President Bush announces restrictions on U.S. federal funding for new embryonic stem cell lines.

• Oct – China’s Ministry of Science and Technology (MOST) and Ministry of Health issue Ethical Guidelines for Human Embryonic Stem Cell Research, explicitly permitting work using:

• Surplus IVF embryos (<14 days old)

• Fetal tissue from voluntary abortions (with consent)

• Somatic cell nuclear transfer (SCNT) for research

• Several Chinese labs, notably at Peking University, Shanghai Second Medical University, and the Chinese Academy of Sciences, begin new derivation projects.

🔹 2002

• Shanghai Second Medical University announces the derivation of multiple new human embryonic stem cell (hESC) lines, including some from fetal germ cells.

• Early reports in Chinese journals describe successful differentiation of hESCs into neuronal precursor cells.

🔹 2003

• Researchers at Peking University develop hESC lines from fetal tissue obtained via therapeutic abortions, isolating neural stem cells capable of differentiating into dopamine-producing neurons (a target for Parkinson’s research).

• Cell Research publishes one of the first comprehensive reports of hESC lines derived entirely within China.

🔹 2004

• A team at the Chinese Academy of Sciences in Shanghai publishes methods for growing stable hESC lines and differentiating them into cardiomyocytes and neural cells.

• International collaboration: Some U.S. and European scientists obtain Chinese hESC lines through joint projects, bypassing Bush-era restrictions.

🔹 2005

• Chinese scientists report in Stem Cells journal that fetal-derived neural stem cells survived and integrated into rat spinal cords, showing partial functional recovery.

• Shanghai groups announce somatic cell nuclear transfer (SCNT)–based embryonic stem cell derivation in primates, something U.S. federal labs could not pursue with federal funding.

🔹 2006

• Cell Research publishes studies on directing fetal-derived stem cells to differentiate into insulin-producing cells for diabetes models.

• Clinical pilot studies begin in China using fetal neural stem cell grafts in patients with spinal cord injury and cerebral palsy — controversial internationally, but legal under Chinese rules.

🔹 2007

• Reports emerge of fetal mesenchymal stem cells (from aborted fetuses) used experimentally to treat liver cirrhosis in small human trials in Beijing and Guangzhou.

• Chinese labs demonstrate hESC-derived retinal pigment epithelial cells in animal models of blindness.

🔹 2008

• A multicenter group publishes data on human fetal-derived neural stem cells transplanted into patients with traumatic brain injury — claiming safety and modest neurological improvement.

• By this point, China had one of the largest banks of hESC lines in the world, many derived from fetal sources, and was supplying lines for research abroad.

📌 Summary:

During 2001–2008, China’s permissive policies allowed it to:

• Derive new hESC lines from both IVF embryos and aborted fetal tissue.

• Continue SCNT experiments.

• Begin controversial pilot clinical uses of fetal stem cells that were off-limits in the U.S.

• Become a source of cell lines and collaboration for Western scientists constrained by U.S. law.

If you want, I can list specific U.S.–China collaborative projects that arose because of Bush’s restrictions, showing how researchers shifted work overseas to access Chinese fetal stem cell lines. That’s where the political implications get interesting.”

Expand full comment
1 more comment...

No posts